Pyr3
Pyr3 is a potent and selective inhibitor of the TRPC3 ion channel, demonstrating dose-dependent inhibition of TRPC3-mediated calcium entry with an IC50 of 700 nM. This tool compound is widely used in cardiovascular and neurological research to investigate TRPC3 function in cellular signaling pathways, both in vitro and in vivo.
Product Specifications
CAS Number
1160514-60-2
Product Name Alternative
Pyr3, Pyr-3, TRPV Channel, TRP Channel, TRPChannel, TRPC3, TRPVChannel
Field of Research
Pharmacology & Drug Discovery
Purity
>98%
Bioactivity
TRPC3 blocker
Form
Powder
Solubility
Soluble in DMSO (up to 40 mg/ml) .
Smiles
CCOC (=O) c1cnn (c1C (F) (F) F) -c1ccc (NC (=O) C (Cl) =C (Cl) Cl) cc1
Molecular Formula
C16H11Cl3F3N3O3
Molecular Weight
456.64
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
1-[4-[ (2,3,3-Trichloro-1-oxo-2-propen-1-yl) amino]phenyl]-5- (trifluoromethyl) -1H-pyrazole-4-carboxylic acid
Available Sizes
Frequently Asked Questions
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