Pyr6
Pyr6 is a selective TRPC3 channel inhibitor with an IC50 of 0.49 μM, demonstrating higher potency against CRAC-mediated calcium entry. This compound is a valuable research tool for studying receptor-operated calcium signaling in cellular models, including mast cell and immune cell research.
Product Specifications
CAS Number
245747-08-4
Product Name Alternative
Inhibitor, N-[4-[3,5-Bis (trifluoromethyl) -1H-pyrazol-1-yl]phenyl]-3-fluoro-4-pyridinecarboxamide, Pyr 6, Pyr6, Pyr-6, inhibit, Transient receptor potential channels, TRP Channel, TRPC3, TRPChannel, TRPVChannel, TRPV Channel
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Purity
98.89% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:10 mg/mL (23.91 mM) ; DMSO:95 mg/mL (227.13 mM)
Smiles
Fc1cnccc1C (=O) Nc1ccc (cc1) -n1nc (cc1C (F) (F) F) C (F) (F) F
Molecular Formula
C17H9F7N4O
Molecular Weight
418.27
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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