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PYZD-4409

PYZD-4409 is a selective UBA1 inhibitor (IC50 = 20 μM) that preferentially induces cell death in malignant cells over normal hematopoietic cells. It is a valuable research tool for studying ubiquitination pathways in oncology, with applications in both in vitro and in vivo cancer models.

Product Specifications

CAS Number

423148-78-1

Product Name Alternative

Inhibit, Inhibitor, E3Enzyme, E3 ligating enzyme, E2Enzyme, E3 Enzyme, E1 activating enzyme, E1/E2/E3 Enzyme, E1 Enzyme, E2 Enzyme, E1Enzyme, E2 conjugating enzyme, Ubiquitin ligase, ubiquitin-activating enzyme UBA1, Ubiquitin conjugating enzyme, Ubiquitin activating enzyme, UBA1, PYZD4409, PYZD-4409, PYZD 4409

Field of Research

Protein Biochemistry

Purity

98.00% (May vary between batches)

Solubility

DMSO:6 mg/mL (17.06 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.84 mM)

Smiles

[O-][N+] (=O) c1ccc (\C=C2\C (=O) NN (C2=O) c2ccc (F) c (Cl) c2) o1

Molecular Formula

C14H7ClFN3O5

Molecular Weight

351.67

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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