PYZD-4409
PYZD-4409 is a selective UBA1 inhibitor (IC50 = 20 μM) that preferentially induces cell death in malignant cells over normal hematopoietic cells. It is a valuable research tool for studying ubiquitination pathways in oncology, with applications in both in vitro and in vivo cancer models.
Product Specifications
CAS Number
423148-78-1
Product Name Alternative
Inhibit, Inhibitor, E3Enzyme, E3 ligating enzyme, E2Enzyme, E3 Enzyme, E1 activating enzyme, E1/E2/E3 Enzyme, E1 Enzyme, E2 Enzyme, E1Enzyme, E2 conjugating enzyme, Ubiquitin ligase, ubiquitin-activating enzyme UBA1, Ubiquitin conjugating enzyme, Ubiquitin activating enzyme, UBA1, PYZD4409, PYZD-4409, PYZD 4409
Field of Research
Protein Biochemistry
Purity
98.00% (May vary between batches)
Solubility
DMSO:6 mg/mL (17.06 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.84 mM)
Smiles
[O-][N+] (=O) c1ccc (\C=C2\C (=O) NN (C2=O) c2ccc (F) c (Cl) c2) o1
Molecular Formula
C14H7ClFN3O5
Molecular Weight
351.67
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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