Quarfloxin
Quarfloxin (CX-3543) is a fluoroquinolone-derived anticancer agent that potently inhibits neuroblastoma cell growth by disrupting the nucleolin-G-quadruplex DNA complex in ribosomal DNA. Its application extends to cancer research, where it has been investigated in both in vitro and in vivo models for its mechanism of action and therapeutic potential.
Product Specifications
CAS Number
865311-47-3
Product Name Alternative
CX3543, CX-3543, CX 3543, DNASynthesis, DNA Synthesis, DNA/RNA Synthesis, inhibit, Inhibitor, Quarfloxin, RNA polymerase I, RNA pol I, RNA Synthesis, RNASynthesis
Field of Research
Cell Biology, Molecular Biology
Purity
99.18% (May vary between batches)
Solubility
DMSO:55 mg/mL (90.96 mM) ; H2O:1 mg/mL (1.65 mM)
Smiles
CN1CCC[C@H]1CCNC (=O) c1cn2c3cc4ccccc4cc3oc3c (N4CCC (C4) c4cnccn4) c (F) cc (c23) c1=O
Molecular Formula
C35H33FN6O3
Molecular Weight
604.67
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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