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Quarfloxin

Quarfloxin (CX-3543) is a fluoroquinolone-derived anticancer agent that potently inhibits neuroblastoma cell growth by disrupting the nucleolin-G-quadruplex DNA complex in ribosomal DNA. Its application extends to cancer research, where it has been investigated in both in vitro and in vivo models for its mechanism of action and therapeutic potential.

Product Specifications

CAS Number

865311-47-3

Product Name Alternative

CX3543, CX-3543, CX 3543, DNASynthesis, DNA Synthesis, DNA/RNA Synthesis, inhibit, Inhibitor, Quarfloxin, RNA polymerase I, RNA pol I, RNA Synthesis, RNASynthesis

Field of Research

Cell Biology, Molecular Biology

Purity

99.18% (May vary between batches)

Solubility

DMSO:55 mg/mL (90.96 mM) ; H2O:1 mg/mL (1.65 mM)

Smiles

CN1CCC[C@H]1CCNC (=O) c1cn2c3cc4ccccc4cc3oc3c (N4CCC (C4) c4cnccn4) c (F) cc (c23) c1=O

Molecular Formula

C35H33FN6O3

Molecular Weight

604.67

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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