Risdiplam
Risdiplam (RG7916) is an orally available small molecule that modifies SMN2 pre-mRNA splicing, elevating survival motor neuron (SMN) protein levels throughout the body. It is widely used in preclinical in vitro and in vivo research for spinal muscular atrophy (SMA), investigating therapeutic mechanisms and efficacy.
Product Specifications
CAS Number
1825352-65-5
Product Name Alternative
DNA Synthesis, DNA/RNA Synthesis, DNASynthesis, Inhibitor, inhibit, SMN2, RG7916, RG-7916, RG 7916, RNA Synthesis, RNASynthesis, Risdiplam, RO 7034067, RO7034067, RO-7034067
Field of Research
Cell Biology, Molecular Biology, Pharmacology & Drug Discovery
Purity
97.46% (May vary between batches)
Solubility
H2O:2.22 mg/mL (5.53 mM) ; Ethanol:2 mg/mL (4.98 mM) ; DMSO:< 1 mg/mL (insoluble or slightly soluble)
Smiles
Cc1cn2nc (cc (C) c2n1) -c1cc (=O) n2cc (ccc2n1) N1CCNC2 (CC2) C1
Molecular Formula
C22H23N7O
Molecular Weight
401.46
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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