RK-287107
RK-287107 is a potent and selective tankyrase inhibitor, demonstrating IC50 values of 14.3 nM and 10.6 nM against tankyrase-1 and tankyrase-2, respectively. This small molecule is a valuable research tool for studying Wnt/β-catenin signaling in cancer biology and has been utilized in both cellular and in vivo models.
Product Specifications
CAS Number
2171386-10-8
Product Name Alternative
PARP, inhibit, Inhibitor, tankyrase 1, tankyrase 2, tankyrase-1, tankyrase-2, RK 287107, RK287107, RK-287107, poly ADP ribose polymerase
Field of Research
Epigenetics & Chromatin, Molecular Biology
Purity
99.59% (May vary between batches)
Solubility
DMSO:120 mg/mL (288.14 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (9.6 mM)
Smiles
OCCN1CC2 (CCN (CC2) c2nc3CCCCc3c (=O) [nH]2) c2c1cc (F) cc2F
Molecular Formula
C22H26F2N4O2
Molecular Weight
416.46
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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