RN-1747
RN-1747 is a selective TRPV4 channel agonist with EC50 values of 0.77 μM (human), 4.0 μM (mouse), and 4.1 μM (rat), and also acts as a TRPM8 antagonist (IC50: 4 μM) . This compound is a valuable research tool for investigating TRP channel physiology in models of pain, osmoregulation, and respiratory function in both cellular and animal studies.
Product Specifications
CAS Number
1024448-59-6
Product Name Alternative
RTRPV4, RN1747, RN-1747, RN 1747, TRP Channel, TRPChannel, TRPV Channel, TRPM8, TRPVChannel, Transient receptor potential channels, mTRPV4, inhibit, hTRPV4, Inhibitor
Field of Research
Pharmacology & Drug Discovery
Purity
99.29% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.05 mM) ; DMSO:55 mg/mL (138.94 mM)
Smiles
[O-][N+] (=O) C1=C (C=CC (Cl) =C1) S (=O) (=O) N1CCN (CC2=CC=CC=C2) CC1
Molecular Formula
C17H18ClN3O4S
Molecular Weight
395.86
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
029028 100 µg
Ap2m1 (AP-2 Complex Subunit mu, AP-2 mu Chain, Adapter-related Protein Complex 2 mu Subunit, Adaptor Protein Complex AP-2 Subunit mu, Clathrin Assembly Protein Complex 2 Medium Chain, Clathrin Coat Assembly Protein AP50, Clathrin Coat-associated Protein AP50, Mu2-adaptin, Plasma Membrane Adaptor AP-2 50kD Protein)
Sign In for Pricing
View Details 
EK345012 96 Well
Porcine SRP9 (Signal Recognition Particle 9kDa) ValidElisa Kit
Sign In for Pricing
View Details 
MBS6450796-01 0.1 mL
DAP3 (Death Associated Protein 3, DAP-3, DKFZp686G12159, MGC126058, MGC126059, MRP-S29, MRPS29, bMRP-10) (Biotin)
Sign In for Pricing
View Details MBS6450796-02 5x 0.1 mL
DAP3 (Death Associated Protein 3, DAP-3, DKFZp686G12159, MGC126058, MGC126059, MRP-S29, MRPS29, bMRP-10) (Biotin)
Sign In for Pricing
View Details