MART-1/Melan-A/MLANA (Melanoma Marker)
Product Specifications
Gene Name
[MLANA]
NCBI Gene ID
2315
Reactivity
Human, Mouse, Rat. Others not tested.
Storage Conditions
Antibody with azide - store at 2 to 8 °C.<br>Antibody without azide - store at -20 to -80 °C.<br>Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Specificity
This antibody recognizes a protein doublet of 20-22kDa, identified as MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Seven other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. This antibody labels melanomas and other tumors showing melanocytic differentiation. It is also a useful positive-marker for angiomyolipomas. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.
Other Gene Names
[MLANA; MLANA; MART1; MART-1; MART1; MART-1]
Short Name
[MART-1/Melan-A/MLANA]
Other Product Names
[melanoma antigen recognized by T-cells 1; Melanoma antigen recognized by T-cells 1; melanoma antigen recognized by T-cells 1; melan-A; Antigen LB39-AA; Antigen SK29-AA; Protein Melan-A]
NCBI GI Number
5031913
NCBI Accession Number
NP_005502.1
NCBI GB Accession Number
NM_005511.1
Uniprot Accession Number
Q16655
Available Sizes
Curated Selection
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