RO9021
RO9021 is a potent and orally bioavailable small molecule inhibitor targeting spleen tyrosine kinase (SYK) with an average IC50 of 5.6 nM. It serves as a valuable research tool for investigating SYK-dependent signaling pathways in both cellular assays and in vivo models of immunology and oncology.
Product Specifications
CAS Number
1446790-62-0
Product Name Alternative
Inhibit, Inhibitor, RO9021, RO-9021, RO 9021, SYK, Syk, Spleen tyrosine kinase
Field of Research
Cardiovascular Research, Signal Transduction
Purity
97.19% (May vary between batches)
Solubility
DMSO:3 mg/mL (8.44 mM)
Smiles
Cc1ccc (Nc2cc (N[C@@H]3CCCC[C@@H]3N) nnc2C (N) =O) nc1C
Molecular Formula
C18H25N7O
Molecular Weight
355.44
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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