Rottlerin
Rottlerin (NSC-56346), a natural compound from Mallotus philippinensis, is a selective PKCδ inhibitor (IC50 3-6 μM) that induces apoptosis through caspase-3 activation. It is widely used in biochemical research to study PKC isoform-specific signaling and programmed cell death in various cancer and cellular models.
Product Specifications
CAS Number
82-08-6
Product Name Alternative
CKII, CaM kinase III, Autophagy, Apoptosis, Mallotoxin, HIV, HIVProtease, HIV Protease, Human immunodeficiency virus, inhibit, NSC56346, NSC-56346, NSC 56346, NSC 94525, Inhibitor, NSC94525, NSC-94525, PKA, PKC, PKCα, PKCβ, PKCγ, PKCδ, PKCε, PKCζ, PKCη, Protein kinase C, Rottlerin
Field of Research
Cell Biology, Neuroscience
Purity
>96%
Bioactivity
Autophagy inducer
Form
Powder
Solubility
Soluble in DMSO (up to 50 mg/ml) .
Smiles
CC (=O) c1c (O) c (C) c (O) c (Cc2c (O) c3C=CC (C) (C) Oc3c (C (=O) \C=C\c3ccccc3) c2O) c1O
Molecular Formula
C30H28O8
Molecular Weight
516.65
Storage Conditions
RT
Notes
For research use only.
Other Product Names
3'-[ (8-Cinnamoyl-5,7-dihydroxy-2,2-dimethyl-2H-1-benzopyran-6-yl) methyl]-2',4',6'-trihydroxy-5'-methylacetophenone
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