Rucaparib monocamsylate
Rucaparib camsylate is a potent PARP inhibitor with a Ki of 1.4 nM for PARP1 and affinity for eight other PARP family members. It is widely used in vitro and in vivo for cancer research, particularly in studies of BRCA-deficient tumors and synthetic lethality.
Product Specifications
CAS Number
1859053-21-6
Product Name Alternative
BRCA2, Capan-1, BRCA1, AG14644, AG014699 monocamsylate, inhibit, MX-1, PARP, PARP1, PARP-1, NF-κB, poly ADP ribose polymerase, Inhibitor, H6PD, SSB, repair, Rucaparib Camsylate, Rucaparib monocamsylate, PF-01367338 monocamsylate
Field of Research
Epigenetics & Chromatin, Molecular Biology, Pharmacology & Drug Discovery
Purity
99.80% (May vary between batches)
Solubility
DMSO:82.33 mg/mL (148.17 mM) ;10% DMSO+40% PEG300+5% Tween-80+45% Saline:3.3 mg/mL (5.94 mM)
Smiles
[H][C@@]12CC[C@@] (CS (O) (=O) =O) (C (=O) C1) C2 (C) C.CNCc1ccc (cc1) -c1[nH]c2cc (F) cc3C (=O) NCCc1c23
Molecular Formula
C29H34FN3O5S
Molecular Weight
555.66
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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