AIF1/Iba1 (Microglia Marker)
Product Specifications
Gene Name
[AIF1]
NCBI Gene ID
199
Reactivity
Human. Others not known.
Storage Conditions
Antibody with azide - store at 2 to 8 °C.<br>Antibody without azide - store at -20 to -80 °C.<br>Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Specificity
AIF1 is a cytoplasmic, calcium-binding protein that is thought to play a role in macrophage activation and function. AIF1, containing two EF domains, is induced by cytokines and Interferons. In an unstimulated state, AIF1 colocalizes with actin, and upon stimulation, translocates to lamellipodia. It is also a marker of human microglia and is expressed by macrophages in injured skeletal muscle. The gene encoding AIF1 resides in the tumor necrosis factor (TNF) cluster of genes, located in the region represented by the human major histocompatibility complex (MHC).
Other Gene Names
[AIF1; AIF1; IBA1; IRT1; AIF-1; IRT-1; G1; IBA1; AIF-1]
Short Name
[AIF1/Iba1]
Other Product Names
[allograft inflammatory factor 1 isoform 1; Allograft inflammatory factor 1; allograft inflammatory factor 1; allograft inflammatory factor 1; Ionized calcium-binding adapter molecule 1; Protein G1]
NCBI GI Number
974987466
NCBI Accession Number
NP_001305899.1
NCBI GB Accession Number
NM_001318970.1
Uniprot Accession Number
P55008
Available Sizes
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