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RWJ-67657

RWJ-67657 is a selective, orally bioavailable inhibitor of p38α and p38β MAP kinases with IC50 values of 1 μM and 11 μM, respectively. It exhibits cardioprotective properties and is utilized in research exploring inflammation, cardiovascular disease, and cellular stress responses in both in vitro and in vivo models.

Product Specifications

CAS Number

215303-72-3

Product Name Alternative

Cardio, anti-tumor, Inhibitor, MCF-7, inhibit, JNJ3026582, JNJ-3026582, JNJ 3026582, inflammation, RWJ 67657, RWJ67657, RWJ-67657, protective. Anti-inflammatory, p38α, p38β, p38MAPK, p38 MAPK

Field of Research

Signal Transduction

Purity

98.28% (May vary between batches)

Solubility

DMSO:125 mg/mL (293.77 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (9.4 mM)

Smiles

OCCC#Cc1nc (c (-c2ccncc2) n1CCCc1ccccc1) -c1ccc (F) cc1

Molecular Formula

C27H24FN3O

Molecular Weight

425.5

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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