RWJ-67657
RWJ-67657 is a selective, orally bioavailable inhibitor of p38α and p38β MAP kinases with IC50 values of 1 μM and 11 μM, respectively. It exhibits cardioprotective properties and is utilized in research exploring inflammation, cardiovascular disease, and cellular stress responses in both in vitro and in vivo models.
Product Specifications
CAS Number
215303-72-3
Product Name Alternative
Cardio, anti-tumor, Inhibitor, MCF-7, inhibit, JNJ3026582, JNJ-3026582, JNJ 3026582, inflammation, RWJ 67657, RWJ67657, RWJ-67657, protective. Anti-inflammatory, p38α, p38β, p38MAPK, p38 MAPK
Field of Research
Signal Transduction
Purity
98.28% (May vary between batches)
Solubility
DMSO:125 mg/mL (293.77 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (9.4 mM)
Smiles
OCCC#Cc1nc (c (-c2ccncc2) n1CCCc1ccccc1) -c1ccc (F) cc1
Molecular Formula
C27H24FN3O
Molecular Weight
425.5
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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