What is the catalog number for Desmoglein-3 (Squamous Cell Marker)?

The catalog number for Desmoglein-3 (Squamous Cell Marker) is MBS439919.

What sizes are available for Desmoglein-3 (Squamous Cell Marker)?

Desmoglein-3 (Squamous Cell Marker) is available in the following size(s): 0.02 mg (With BSA & Azide at 0.2mg/mL), 0.1 mg (With BSA & Azide at 0.2mg/mL), 0.1 mg (Without BSA & Azide at 1mg/mL), 5x 0.1 mg (With BSA & Azide at 0.2mg/mL), 5x 0.1 mg (Without BSA & Azide at 1mg/mL).

How many pack sizes does Desmoglein-3 (Squamous Cell Marker) come in?

Desmoglein-3 (Squamous Cell Marker) is available in 5 different pack sizes.

Is Desmoglein-3 (Squamous Cell Marker) in stock?

Desmoglein-3 (Squamous Cell Marker) is currently made to order / not held in immediate stock. Contact us for lead time.

Desmoglein-3 (Squamous Cell Marker)

Product Specifications

Gene Name

[DSG3]

NCBI Gene ID

1830

Reactivity

Human. Others not known.

Storage Conditions

Antibody with azide - store at 2 to 8 °C.<br>Antibody without azide - store at -20 to -80 °C.<br>Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Specificity

Recognizes a protein of 130kDa, identified as Desmoglein-3 (DSG3). This MAb is highly specific to Desmoglein-3 and does not cross-react with other members of the Desmoglein-family. DSG3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Research has shown that DSG3 has a very high sensitivity (>80%) and specificity (100%) in recognizing squamous cell carcinoma (SqCC). Therefore, DSG3 is considered a very important marker for lung SqCC and can be a useful ancillary marker to separate SqCC from other subtypes of lung cancer. Moreover, studies have shown that DSG3 expression in lung SqCC may indicate a poor prognosis.