Desmoglein-3 (Squamous Cell Marker)
Product Specifications
Gene Name
[DSG3]
NCBI Gene ID
1830
Reactivity
Human. Others not known.
Storage Conditions
Antibody with azide - store at 2 to 8 °C.<br>Antibody without azide - store at -20 to -80 °C.<br>Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Specificity
Recognizes a protein of 130kDa, identified as Desmoglein-3 (DSG3). This MAb is highly specific to Desmoglein-3 and does not cross-react with other members of the Desmoglein-family. DSG3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Currently, three desmoglein subfamily members are identified and all are members of the cadherin cell adhesion molecule superfamily.
Other Gene Names
[DSG3; DSG3; PVA; CDHF6; CDHF6; PVA]
Short Name
[Desmoglein-3]
Other Product Names
[desmoglein-3 preproprotein; Desmoglein-3; desmoglein-3; desmoglein 3; 130 kDa pemphigus vulgaris antigen; PVA; Cadherin family member 6]
NCBI GI Number
119964718
NCBI Accession Number
NP_001935.2
NCBI GB Accession Number
NM_001944.2
Uniprot Accession Number
P32926
Available Sizes
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