S18-000003
S18-000003 is a potent and orally bioavailable RORγt inhibitor with an IC50 of 29 nM. It effectively suppresses IL-17 production, making it a valuable tool for researching Th17-driven pathologies in both cellular and animal models of autoimmune and inflammatory diseases.
Product Specifications
CAS Number
2068119-11-7
Product Name Alternative
Inhibitor, inhibit, orphan, acid, aberrations, RAR-related orphan receptor, receptor-related, thymic, psoriasis, retinoic, ROR, RORγt, S18 000003, S18000003, S-18-000003, S18-000003
Field of Research
Metabolism Research
Purity
99.24% (May vary between batches)
Solubility
DMSO:100 mg/mL (192.85 mM)
Smiles
CCS (=O) (=O) c1ccc (CC (=O) Nc2ccc (c (F) c2) C (C) (C) C (=O) Nc2ccc (F) cc2F) cc1
Molecular Formula
C26H25F3N2O4S
Molecular Weight
518.55
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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