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S18-000003

S18-000003 is a potent and orally bioavailable RORγt inhibitor with an IC50 of 29 nM. It effectively suppresses IL-17 production, making it a valuable tool for researching Th17-driven pathologies in both cellular and animal models of autoimmune and inflammatory diseases.

Product Specifications

CAS Number

2068119-11-7

Product Name Alternative

Inhibitor, inhibit, orphan, acid, aberrations, RAR-related orphan receptor, receptor-related, thymic, psoriasis, retinoic, ROR, RORγt, S18 000003, S18000003, S-18-000003, S18-000003

Field of Research

Metabolism Research

Purity

99.24% (May vary between batches)

Solubility

DMSO:100 mg/mL (192.85 mM)

Smiles

CCS (=O) (=O) c1ccc (CC (=O) Nc2ccc (c (F) c2) C (C) (C) C (=O) Nc2ccc (F) cc2F) cc1

Molecular Formula

C26H25F3N2O4S

Molecular Weight

518.55

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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