S26131
S26131 is a potent and selective melatonin receptor antagonist, exhibiting high affinity for MT1 (Ki = 0.5 nM) and lower affinity for MT2 (Ki = 112 nM) . This small molecule is a valuable research tool for investigating circadian rhythms, sleep disorders, and cancer biology in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
296280-56-3
Product Name Alternative
Antagonist, ligand, MTReceptor, inhibit, MT1 receptor, MT Receptor, MT2 receptor, MT2, N-[2-[7-[3-[8- (2-acetamidoethyl) naphthalen-2-yl]oxypropoxy]naphthalen-1-yl]ethyl]acetamide, Inhibitor, Melatonin Receptor, melatoninergic, S 26131, S26131, S-26131, selectively
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
99.69% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.01 mM) ; DMSO:25 mg/mL (50.14 mM)
Smiles
CC (=O) NCCc1cccc2ccc (OCCCOc3ccc4cccc (CCNC (C) =O) c4c3) cc12
Molecular Formula
C31H34N2O4
Molecular Weight
498.61
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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