SAR-260301
SAR-260301 is a potent and selective small molecule inhibitor of PI3Kβ, exhibiting an IC50 of 23 nM and oral bioavailability. It is a valuable research tool for studying PI3Kβ signaling in oncology and thrombosis, applicable in both cellular assays and in vivo models.
Product Specifications
CAS Number
1260612-13-2
Product Name Alternative
DNA-PK, pAkt, PI3Kδ, PI3Kβ, PI3Kγ, PI3Kα, PI3KC2γ, SAR260301, SAR-260301, SAR 260301, Vps34
Field of Research
Signal Transduction
Purity
98.65% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (11.29 mM) ; DMSO:125 mg/mL (352.71 mM)
Smiles
C[C@H]1Cc2ccccc2N1C (=O) Cc1nc (cc (=O) [nH]1) N1CCOCC1
Molecular Formula
C19H22N4O3
Molecular Weight
354.4
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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