SB-222200
SB-222200 is a potent and selective competitive antagonist of the human neurokinin-3 (NK-3) receptor, exhibiting a Ki of 4.4 nM. It is a valuable research tool for studying NK-3 receptor function in both in vitro assays and in vivo models related to reproduction, anxiety, and gastrointestinal motility.
Product Specifications
CAS Number
174635-69-9
Product Name Alternative
Inhibitor, inhibit, NK receptor, NK3, NK-3R, NKB, Neurokinin receptor, neurokinin-B, Neurokininreceptor, Neurokinin Receptor, nervous, central, CNS, disorders, penetrant, SB 222200, SB222200, SB-222200, system, Tachykinin receptor
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
97.13% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (10.51 mM) ; DMSO:100 mg/mL (262.83 mM)
Smiles
C (N[C@@H] (CC) C1=CC=CC=C1) (=O) C=2C3=C (N=C (C2C) C4=CC=CC=C4) C=CC=C3
Molecular Formula
C26H24N2O
Molecular Weight
380.48
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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