Catenin, alpha-1 (CTNNA1)
Product Specifications
Gene Name
[CTNNA1]
NCBI Gene ID
1495
Reactivity
Human. Others not known.
Storage Conditions
Antibody with azide - store at 2 to 8 °C.<br>Antibody without azide - store at -20 to -80 °C.<br>Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Specificity
Recognizes a protein of 102kDa, identified as Catenin, alpha-1. Catenins comprise a large family of Ca2+-dependent, homotypic cell-cell adhesion molecules that play important roles in development, epithelial cell polarity and tumor progression. Alpha-catenin is a key regulator of actin dynamics in cell-cell adhesion. During cell-cell adhesion, alpha-catenin forms a heterodimer with beta-catenin and links the cadherins to actin associated with the cytoskeleton. Alpha-catenin also regulates the beta-catenin signaling in various cells. It displays the tumor suppressor activity and is found to be down regulated in some forms of breast cancer.
Other Gene Names
[CTNNA1; CTNNA1; MDPT2; CAP102]
Short Name
[Catenin, alpha-1 (CTNNA1)]
Other Product Names
[catenin alpha-1 isoform 2; Catenin alpha-1; catenin alpha-1; catenin alpha 1; Alpha E-catenin; Cadherin-associated protein; Renal carcinoma antigen NY-REN-13]
NCBI GI Number
594140506
NCBI Accession Number
NP_001277236.1
NCBI GB Accession Number
NM_001290307.2
Uniprot Accession Number
P35221
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
