SBI-553
SBI-553 is a potent, brain-penetrant allosteric modulator of the neurotensin receptor 1 (NTR1) with an EC50 of 0.34 μM. It is a valuable research tool for investigating NTR1 function in neurological disorders and is suitable for both in vitro binding assays and in vivo behavioral studies.
Product Specifications
CAS Number
1849603-72-0
Product Name Alternative
Inhibit, Neurotensin Receptor, NeurotensinReceptor, NTR1, Inhibitor, SBI553, SBI-553, SBI 553
Field of Research
Neuroscience
Purity
>98%
Form
Powder
Solubility
Soluble in DMSO (up to at least 12 mg/ml)
Smiles
COc1ccccc1C1CCN (CC1) c1nc (nc2ccc (cc12) N (C) CCO) C1 (F) CC1
Molecular Formula
C26H31FN4O2
Molecular Weight
450.6
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
2-[[2- (1-Fluorocyclopropyl) -4-[4- (2-methoxyphenyl) piperidin-1-yl) quinazolin-6-yl]methylamino]ethanol
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