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SBI-553

SBI-553 is a potent, brain-penetrant allosteric modulator of the neurotensin receptor 1 (NTR1) with an EC50 of 0.34 μM. It is a valuable research tool for investigating NTR1 function in neurological disorders and is suitable for both in vitro binding assays and in vivo behavioral studies.

Product Specifications

CAS Number

1849603-72-0

Product Name Alternative

Inhibit, Neurotensin Receptor, NeurotensinReceptor, NTR1, Inhibitor, SBI553, SBI-553, SBI 553

Field of Research

Neuroscience

Purity

>98%

Form

Powder

Solubility

Soluble in DMSO (up to at least 12 mg/ml)

Smiles

COc1ccccc1C1CCN (CC1) c1nc (nc2ccc (cc12) N (C) CCO) C1 (F) CC1

Molecular Formula

C26H31FN4O2

Molecular Weight

450.6

Storage Conditions

-20°C

Notes

For research use only.

Other Product Names

2-[[2- (1-Fluorocyclopropyl) -4-[4- (2-methoxyphenyl) piperidin-1-yl) quinazolin-6-yl]methylamino]ethanol

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