SEC inhibitor KL-1
KL-1 is a potent and selective super elongation complex (SEC) inhibitor that disrupts the AFF4-CCNT1 interaction with a Ki of 3.48 μM. This small molecule is a valuable chemical probe for studying transcriptional control in cancers and HIV latency reversal in both cellular and biochemical assays.
Product Specifications
CAS Number
900308-84-1
Product Name Alternative
SEC inhibitor KL-1, SEC, SEC inhibitor KL 1, SEC inhibitor KL1, KL1, KL-1, KL 1
Field of Research
Cell Biology, Pharmacology & Drug Discovery
Purity
97.42% (May vary between batches)
Solubility
10% DMSO+90% Corn Oil:2 mg/mL (5.78 mM) ; DMSO:41.67 mg/mL (120.51 mM)
Smiles
COc1cccc (c1) C (=O) \C=C (/O) C (=O) Nc1cc (Cl) ccc1C
Molecular Formula
C18H16ClNO4
Molecular Weight
345.78
Storage Conditions
-20°C
Notes
For research use only.
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