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SEC inhibitor KL-1

KL-1 is a potent and selective super elongation complex (SEC) inhibitor that disrupts the AFF4-CCNT1 interaction with a Ki of 3.48 μM. This small molecule is a valuable chemical probe for studying transcriptional control in cancers and HIV latency reversal in both cellular and biochemical assays.

Product Specifications

CAS Number

900308-84-1

Product Name Alternative

SEC inhibitor KL-1, SEC, SEC inhibitor KL 1, SEC inhibitor KL1, KL1, KL-1, KL 1

Field of Research

Cell Biology, Pharmacology & Drug Discovery

Purity

97.42% (May vary between batches)

Solubility

10% DMSO+90% Corn Oil:2 mg/mL (5.78 mM) ; DMSO:41.67 mg/mL (120.51 mM)

Smiles

COc1cccc (c1) C (=O) \C=C (/O) C (=O) Nc1cc (Cl) ccc1C

Molecular Formula

C18H16ClNO4

Molecular Weight

345.78

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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