Clathrin, Light Chain
Product Specifications
Gene Name
[CLTA]
NCBI Gene ID
1211
Reactivity
Human. Others not known.
Storage Conditions
Antibody with azide - store at 2 to 8 °C.<br>Antibody without azide - store at -20 to -80 °C.<br>Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Specificity
Recognizes proteins of 31-44kDa, which are identified as Clathrin Light Chains (both A & B). Clathrin is composed of three heavy chains and three light chains, which associate non-covalently to form a triskelion structure. Clathrin light chain regulates the self-assembly of triskelions onto intracellular membranes. Clathrin light chain subunits (LCA and LCB) contribute to regulation of coated vesicle formation to sort proteins during receptor-mediated endocytosis and organelle biogenesis. LCA and LCB are encoded by two discrete genes. They share only 60% homology, and have certain features in common. Both LCA and LCB undergo alternative mRNA splicing, which results in the generation of tissue-specific isoforms.
Other Gene Names
[CLTA; CLTA; LCA; Lca]
Short Name
[Clathrin, Light Chain]
Other Product Names
[clathrin light chain A isoform c; Clathrin light chain A; clathrin light chain A; clathrin light chain A]
NCBI GI Number
115527060
NCBI Accession Number
NP_001070145.1
NCBI GB Accession Number
NM_001076677.2
Uniprot Accession Number
P09496
Available Sizes
Curated Selection
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