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Clathrin, Light Chain

Product Specifications

Gene Name

[CLTA]

NCBI Gene ID

1211

Reactivity

Human. Others not known.

Storage Conditions

Antibody with azide - store at 2 to 8 °C.<br>Antibody without azide - store at -20 to -80 °C.<br>Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Specificity

Recognizes proteins of 31-44kDa, which are identified as Clathrin Light Chains (both A & B). Clathrin is composed of three heavy chains and three light chains, which associate non-covalently to form a triskelion structure. Clathrin light chain regulates the self-assembly of triskelions onto intracellular membranes. Clathrin light chain subunits (LCA and LCB) contribute to regulation of coated vesicle formation to sort proteins during receptor-mediated endocytosis and organelle biogenesis. LCA and LCB are encoded by two discrete genes. They share only 60% homology, and have certain features in common. Both LCA and LCB undergo alternative mRNA splicing, which results in the generation of tissue-specific isoforms.

Other Gene Names

[CLTA; CLTA; LCA; Lca]

Short Name

[Clathrin, Light Chain]

Other Product Names

[clathrin light chain A isoform c; Clathrin light chain A; clathrin light chain A; clathrin light chain A]

NCBI GI Number

115527060

NCBI Accession Number

NP_001070145.1

NCBI GB Accession Number

NM_001076677.2

Uniprot Accession Number

P09496

Available Sizes

Frequently Asked Questions

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