Podoplanin (PDPN) (Lymphatic Endothelial & Mesothelial Marker)
Product Specifications
Gene Name
[PDPN]
NCBI Gene ID
10630
Reactivity
Human. Others not known.
Storage Conditions
Antibody with azide - store at 2 to 8 °C.<br>Antibody without azide - store at -20 to -80 °C.<br>Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Specificity
It recognizes a muco-protein of 38-43kDa, which is identified Podoplanin (PDPN). It localizes in stromal cells of peripheral lymphoid tissue and thymic epithelial cells. As a regulator of the lymphatic endothelium, podoplanin probably plays a role in maintaining the unique shape of podocytes. It is selectively expressed in lymphatic endothelium as well as lymphoangiomas, Kaposi sarcomas, and in a subset of angiosarcomas with probable lymphatic differentiation. Recent studies have also shown podoplanin to be a highly sensitive and relatively specific marker for epithelioid mesothelioma. Therefore, it can be used in a panel to distinguish mesotheliomas or mesothelial cells from pulmonary carcinomas.
Other Gene Names
[PDPN; PDPN; T1A; GP36; GP40; Gp38; OTS8; T1A2; TI1A; T1A-2; AGGRUS; HT1A-1; PA2.26; PICD]
Short Name
[Podoplanin (PDPN)]
Other Product Names
[podoplanin isoform c; Podoplanin; podoplanin; podoplanin; Aggrus]
NCBI GI Number
54792060
NCBI Accession Number
NP_001006625.1
NCBI GB Accession Number
NM_001006624.1
Uniprot Accession Number
Q86YL7
Available Sizes
Curated Selection
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