SRT 2183
SRT 2183 is a potent and selective small molecule activator of Sirtuin-1 (SIRT1), exhibiting an EC1.5 of 0.36 μM. It is widely used in biochemical and cellular research to study SIRT1's role in aging, metabolism, and neurodegenerative diseases, with applications in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
1001908-89-9
Product Name Alternative
Inhibit, Inhibitor, Apoptosis, SIRT1, Sirtuin, SRT2183, SRT-2183, SRT 2183
Field of Research
Cell Biology, Epigenetics & Chromatin, Molecular Biology
Purity
97.86% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (10.67 mM) ; DMSO:240 mg/mL (512.2 mM)
Smiles
O[C@@H]1CCN (Cc2csc3nc (cn23) -c2ccccc2NC (=O) c2ccc3ccccc3c2) C1
Molecular Formula
C27H24N4O2S
Molecular Weight
468.57
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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