CDX2 (GI Epithelial Marker)
Product Specifications
Gene Name
[CDX2]
NCBI Gene ID
1045
Reactivity
Human. Others not known.
Storage Conditions
Antibody with azide - store at 2 to 8 °C.<br>Antibody without azide - store at -20 to -80 °C.<br>Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Specificity
The intestine-specific transcription factors CDX1 and CDX2 are important for directing intestinal development, differentiation, proliferation and maintenance of the intestinal phenotype. CDX2 protein expression has been seen in GI carcinomas. Anti-CDX2 has been useful to establish GI origin of metastatic adenocarcinomas and carcinoids and is especially useful to distinguish metastatic colorectal adenocarcinoma from lung adenocarcinoma. However, mucinous carcinomas of the ovary also express CDX2 protein. It limits the usefulness of this marker in the distinction of metastatic colorectal adenocarcinoma from mucinous carcinoma of the ovary.
Other Gene Names
[CDX2; CDX2; CDX3; CDX-3; CDX2/AS; CDX3]
Short Name
[CDX2]
Other Product Names
[homeobox protein CDX-2 isoform 1; Homeobox protein CDX-2; homeobox protein CDX-2; caudal type homeobox 2; CDX-3; Caudal-type homeobox protein 2]
NCBI GI Number
372624392
NCBI Accession Number
NP_001256.3
NCBI GB Accession Number
NM_001265.5
Uniprot Accession Number
Q99626
Available Sizes
Curated Selection
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