CD30 / TNFRSF8 (Hodgkin & Reed-Sternberg Cell Marker) Mouse Monoclonal Antibody
Product Specifications
Gene Name
[TNFRSF8]
NCBI Gene ID
943
Reactivity
Human
Storage Conditions
Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Specificity
Recognizes a single chain glycoprotein of 105/120kDa, identified as CD30/Ki-1. CD30 is synthesized as a 90kDa precursor, which is processed in the Golgi complex into a membrane-bound phosphorylated mature 105/120kDa glycoprotein. In Hodgkin's disease, CD30/Ki-1 antigen is expressed by mononuclear-Hodgkin and multinucleated Reed-Sternberg cells. It is also expressed by the tumor cells of a majority of anaplastic large cell lymphomas as well as by a varying proportion of activated T and B cells. This MAb distinguishes large cell lymphomas derived from activated lymphoid cells from histiocytic malignancies and lymphomas derived from resting and precursor lymphoid cells or from anaplastic carcinomas. About one third of the Ki-1 positive lymphomas lack the leukocyte common antigen (CD45).
Other Gene Names
[TNFRSF8; TNFRSF8; CD30; Ki-1; D1S166E; CD30; D1S166E]
Short Name
[CD30 / TNFRSF8]
Other Product Names
[tumor necrosis factor receptor superfamily member 8 isoform 1; Tumor necrosis factor receptor superfamily member 8; tumor necrosis factor receptor superfamily member 8; TNF receptor superfamily member 8; CD30L receptor; Ki-1 antigen; Lymphocyte activation antigen CD30; CD_antigen: CD30]
NCBI GI Number
597709795
NCBI Accession Number
NP_001234.3
NCBI GB Accession Number
NM_001243.4
Uniprot Accession Number
P28908
CAS Number
9007-83-4
Available Sizes
Curated Selection
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