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TAO Kinase inhibitor 1

TAO Kinase inhibitor 1 is a potent, selective ATP-competitive inhibitor of TAOK1 and TAOK2 (IC50 11-15 nM) . It functions by delaying mitotic progression and inducing mitotic cell death, making it a valuable tool for studying cell cycle regulation and apoptosis in cancer research models, both in vitro and in vivo.

Product Specifications

CAS Number

850467-66-2

Product Name Alternative

CP43, CP-43, CP 43, MAP3K, MAP kinase kinase kinase, MEKK, MAPKKK, Inhibitor, inhibit, TAO Kinase inhibitor 1, TAO Kinase inhibitor1, TAO Kinase inhibitor-1, TAOK1, TAOK2

Field of Research

Pharmacology & Drug Discovery, Signal Transduction

Purity

99.45% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.2 mM) ; DMSO:55 mg/mL (143.05 mM)

Smiles

N (C (CNC (=O) C1=CC=C (C=C1) C2=CC=CC=C2) =O) C3C=4C (CCC3) =CC=CC4

Molecular Formula

C25H24N2O2

Molecular Weight

384.47

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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