TAO Kinase inhibitor 1
TAO Kinase inhibitor 1 is a potent, selective ATP-competitive inhibitor of TAOK1 and TAOK2 (IC50 11-15 nM) . It functions by delaying mitotic progression and inducing mitotic cell death, making it a valuable tool for studying cell cycle regulation and apoptosis in cancer research models, both in vitro and in vivo.
Product Specifications
CAS Number
850467-66-2
Product Name Alternative
CP43, CP-43, CP 43, MAP3K, MAP kinase kinase kinase, MEKK, MAPKKK, Inhibitor, inhibit, TAO Kinase inhibitor 1, TAO Kinase inhibitor1, TAO Kinase inhibitor-1, TAOK1, TAOK2
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Purity
99.45% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.2 mM) ; DMSO:55 mg/mL (143.05 mM)
Smiles
N (C (CNC (=O) C1=CC=C (C=C1) C2=CC=CC=C2) =O) C3C=4C (CCC3) =CC=CC4
Molecular Formula
C25H24N2O2
Molecular Weight
384.47
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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