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MUC18 /CD146 / MCAM (Melanoma Cell Adhesion Molecule) Mouse Monoclonal Antibody

Product Specifications

Gene Name

[MCAM]

NCBI Gene ID

4162

Reactivity

Human

Storage Conditions

Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Specificity

The human Mel-CAM gene maps to chromosome 11q23 and encodes a trans-membrane glycoprotein, also designated MCAM, MUC 18 or CD146, that belongs to the immunoglobulin superfamily and functions as a Ca2+-independent cell adhesion molecule. Mel-CAM expression is restricted to advanced primary and metastatic melanomas and to cell lines of the neuroectodermal lineage, but not normal melanocytes. Mel-CAM is found on 80% of advanced primary human melanomas and correlates well with development of metastatic disease.

Other Gene Names

[MCAM; MCAM; CD146; MUC18; MUC18]

Short Name

[MUC18 /CD146 / MCAM (Melanoma Cell Adhesion Molecule)]

Other Product Names

[cell surface glycoprotein MUC18; Cell surface glycoprotein MUC18; cell surface glycoprotein MUC18; melanoma cell adhesion molecule; Cell surface glycoprotein P1H12; Melanoma cell adhesion molecule; Melanoma-associated antigen A32; Melanoma-associated antigen MUC18; S-endo 1 endothelial-associated antigen; CD_antigen: CD146]

NCBI GI Number

71274107

NCBI Accession Number

NP_006491.2

NCBI GB Accession Number

NM_006500.2

Uniprot Accession Number

P43121

CAS Number

9007-83-4

Available Sizes

Curated Selection

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