Pimitespib
Pimitespib (TAS-116) is a potent and selective ATP-competitive inhibitor targeting both HSP90α and HSP90β isoforms. It has demonstrated antitumor activity in preclinical models, supporting its research use in oncology for investigating HSP90's role in protein folding and cancer cell survival.
Product Specifications
CAS Number
1260533-36-5
Product Name Alternative
Heat shock proteins, Inhibitor, HSP, HSP90α, HSP90β, inhibit, Pimitespib, TAS 116, TAS116, TAS-116
Field of Research
Metabolism Research, Signal Transduction
Purity
99.22% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (8.8 mM) ; DMSO:50 mg/mL (110 mM)
Smiles
CCc1cc (ccc1-n1nc (C (C) C) c2c (ccnc12) -n1cnc (c1) -c1cnn (C) c1) C (N) =O
Molecular Formula
C25H26N8O
Molecular Weight
454.53
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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