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Pimitespib

Pimitespib (TAS-116) is a potent and selective ATP-competitive inhibitor targeting both HSP90α and HSP90β isoforms. It has demonstrated antitumor activity in preclinical models, supporting its research use in oncology for investigating HSP90's role in protein folding and cancer cell survival.

Product Specifications

CAS Number

1260533-36-5

Product Name Alternative

Heat shock proteins, Inhibitor, HSP, HSP90α, HSP90β, inhibit, Pimitespib, TAS 116, TAS116, TAS-116

Field of Research

Metabolism Research, Signal Transduction

Purity

99.22% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (8.8 mM) ; DMSO:50 mg/mL (110 mM)

Smiles

CCc1cc (ccc1-n1nc (C (C) C) c2c (ccnc12) -n1cnc (c1) -c1cnn (C) c1) C (N) =O

Molecular Formula

C25H26N8O

Molecular Weight

454.53

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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