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Tazemetostat hydrobromide

Tazemetostat hydrobromide is a potent, selective inhibitor of EZH2 (Ki=2.5 nM) and EZH1 (IC50=392 nM), targeting the PRC2 complex. It is widely used in oncology research to study epigenetic mechanisms in vitro and has demonstrated antitumor efficacy in various preclinical in vivo models.

Product Specifications

CAS Number

1467052-75-0

Product Name Alternative

Tazemetostat, Tazemetostat Hydrobromide, Tazemetostat hydrobromide, Rat EZH2, PRC2, cancer, E 7438, E 7438 Hydrobromide, E-7438, E7438, E7438 Hydrobromide, E-7438 hydrobromide, E-7438 Hydrobromide, inhibit, HistoneMethyltransferase, Histone Methyltransferase, Inhibitor, EZH2, EZH2 WT, EZH1, epigenetic, EPZ 6438, EPZ 6438 Hydrobromide, EPZ6438, EPZ-6438, EPZ6438 Hydrobromide, EPZ-6438 Hydrobromide, EPZ-6438 hydrobromide

Field of Research

Epigenetics & Chromatin, Pharmacology & Drug Discovery

Purity

99.03% (May vary between batches)

Solubility

DMSO:102 mg/mL (156.05 mM)

Smiles

O=C (C1=CC (C2=CC=C (CN3CCOCC3) C=C2) =CC (N (CC) C4CCOCC4) =C1C) NCC5=C (C) C=C (C) NC5=O.[H]Br

Molecular Formula

C34H45BrN4O4

Molecular Weight

653.65

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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