c-Myc Oncoprotein Mouse Monoclonal Antibody
Product Specifications
CAS Number
9007-83-4
Gene Name
[MYC]
NCBI Gene ID
4609
Reactivity
Human.<br>Does not react with Mouse, Rat, and Chicken.<br>Others not tested
Storage Conditions
Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Specificity
It recognizes a transcription factor of 64-67kDa, identified as c-myc. Its epitope spans between aa 410-419 (EQKLISEEDL) which is a specific portion of an alpha helical region of human c-myc protein. This MAb shows no cross-reaction with v-myc. c-myc is involved in the control of cell proliferation and differentiation and is amplified and/or overexpressed in a variety of tumors. Over-expression of c-myc protein occurs frequently in luminal cells of prostate intraepithelial neoplasia as well as in most primary carcinomas and metastatic disease.
Other Gene Names
[MYC; MYC; MRTL; MYCC; c-Myc; bHLHe39; BHLHE39; bHLHe39]
Short Name
[c-Myc Oncoprotein]
Other Product Names
[myc proto-oncogene protein; Myc proto-oncogene protein; myc proto-oncogene protein; v-myc avian myelocytomatosis viral oncogene homolog; Class E basic helix-loop-helix protein 39; bHLHe39; Proto-oncogene c-Myc; Transcription factor p64]
NCBI GI Number
71774083
NCBI Accession Number
NP_002458.2
NCBI GB Accession Number
NM_002467.4
Uniprot Accession Number
P01106
Available Sizes
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