SN-38
SN-38 (NK012) is the active metabolite of the Topoisomerase I inhibitor Irinotecan. It potently inhibits DNA/RNA synthesis and exhibits antitumor activity, including the induction of autophagy, making it a valuable tool for in vitro and in vivo cancer research.
Product Specifications
CAS Number
86639-52-3
Product Name Alternative
ADC Payload, ADC Cytotoxin, ADCCytotoxin, Autophagy, DNA synthesis, DNA Synthesis, DNASynthesis, Inhibitor, inhibit, NK012, NK-012, NK 012, Topoisomerase, Topo I, RNA Synthesis, RNASynthesis, SN 38, SN38, SN-38
Field of Research
Cell Biology, Metabolism Research, Molecular Biology
Purity
>98%
Bioactivity
DNA topoisomerase I inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 40 mg/ml) .
Smiles
C (C) C1=C2C (C=3N (C2) C (=O) C4=C (C3) [C@] (CC) (O) C (=O) OC4) =NC=5C1=CC (O) =CC5
Molecular Formula
C22H20N2O5
Molecular Weight
392.41
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
7-Ethyl-10-hydroxycamptothecin
Available Sizes
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