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TES-1025

TES-1025 is a potent and selective small molecule inhibitor of human ACMSD (α-amino-β-carboxymuconate-ε-semialdehyde decarboxylase), exhibiting an IC50 of 13 nM. This inhibitor is a valuable research tool for studying the kynurenine pathway in models of metabolic and neurological disorders, both in vitro and in vivo.

Product Specifications

CAS Number

1883602-21-8

Product Name Alternative

ACMSD, inhibit, human ACMSD, Inhibitor, TES 1025, TES1025, TES-1025

Purity

98.80% (May vary between batches)

Solubility

DMSO:95 mg/mL (247.76 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (8.61 mM)

Smiles

OC (=O) Cc1cccc (CSc2nc (-c3cccs3) c (C#N) c (=O) [nH]2) c1

Molecular Formula

C18H13N3O3S2

Molecular Weight

383.44

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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