TFMB- (R) -2-HG
TFMB- (R) -2-HG is a cell-permeable form of the oncometabolite (R) -2-hydroxyglutarate. It is used to study the role of this metabolite in acute myeloid leukemia, where it disrupts cellular differentiation pathways, as demonstrated in in vitro models like estrogen-withdrawn SCF ER-Hoxb8 cells.
Product Specifications
CAS Number
1445700-01-5
Product Name Alternative
Carcinogenic factor, inhibit, Inhibitor, TFMB (R) 2 HG, TFMB (R) 2HG, TFMB-2-HG
Field of Research
Epigenetics & Chromatin, Metabolism Research
Purity
97.15% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.94 mM) ; DMSO:55 mg/mL (190.83 mM)
Smiles
FC (F) (F) c1cccc (COC (=O) [C@H]2CCC (=O) O2) c1
Molecular Formula
C13H11F3O4
Molecular Weight
288.22
Storage Conditions
-20°C
Notes
For research use only.
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