CD31 / PECAM-1 (Endothelial Cell Marker) Mouse Monoclonal Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

[PECAM1]

NCBI Gene ID

5175

Reactivity

Human, Cynomolgus Monkey, Rabbit.<br>Does not react with Rat and Pig

Storage Conditions

Antibody with azide - store at 4 to 8 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Specificity

CD31 (PECAM-1) is a transmembrane glycoprotein member of the immunoglobulin supergene family of adhesion molecules. CD31 is expressed by stem cells of the hematopoietic system and is primarily used to identify and concentrate these cells for experimental studies as well as for bone marrow transplantation. Anti-CD31 has shown to be highly specific and sensitive for vascular endothelial cells. Staining of nonvascular tumors (excluding hematopoietic neoplasms) is rare. CD31 MAb reacts with normal, benign, and malignant endothelial cells which make up blood vessel lining. The level of CD31 expression can help to determine the degree of tumor angiogenesis, and a high level of CD31 expression may imply a rapidly growing tumor and potentially a predictor of tumor recurrence.

Other Gene Names

[PECAM1; PECAM1; CD31; PECA1; GPIIA'; PECAM-1; endoCAM; CD31/EndoCAM; PECAM-1]

Short Name

[CD31 / PECAM-1]

Other Product Names

[platelet endothelial cell adhesion molecule; Platelet endothelial cell adhesion molecule; platelet endothelial cell adhesion molecule; platelet and endothelial cell adhesion molecule 1; EndoCAM; GPIIA'; PECA1; CD_antigen: CD31]