Tipifarnib (S enantiomer)
Tipifarnib S enantiomer ((S) - (-) -R-115777) is the S-configured enantiomer of the potent farnesyltransferase inhibitor Tipifarnib, which exhibits an IC50 of 0.6 nM. This compound is used in research to study oncology pathways, particularly in hematologic malignancies and solid tumors, in both cellular and animal models.
Product Specifications
CAS Number
192185-71-0
Product Name Alternative
Tipifarnib, Tipifarnib (S enantiomer), Tipifarnib S enantiomer, R 115777, R115777, R-115777, (S) - (-) -R-115777, (S) -Tipifarnib, inhibit, IND-58359 S enantiomer, Inhibitor, Farnesyl Transferase, Ftase
Field of Research
Metabolism Research
Purity
99.05% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.09 mM) ; DMSO:25 mg/mL (51.08 mM)
Smiles
Cn1cncc1[C@] (N) (c1ccc (Cl) cc1) c1ccc2n (C) c (=O) cc (-c3cccc (Cl) c3) c2c1
Molecular Formula
C27H22Cl2N4O
Molecular Weight
489.4
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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