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Toxoflavin

Toxoflavin (Xanthothricin) is a small molecule that antagonizes the TCF4/β-catenin transcriptional complex and inhibits the histone demethylase KDM4A. It is used in vitro and in vivo to study Wnt/β-catenin signaling and epigenetic regulation in cancer and stem cell research.

Product Specifications

CAS Number

84-82-2

Product Name Alternative

Inhibitor, inhibit, Antibiotic, Bacterial, bcatenin, Beta catenin, betacatenin, beta-catenin, βcatenin, β-catenin, Wnt, PKF-118-310, Wnt/betacatenin, Wnt/b-catenin, Wnt/β-catenin, Xanthothricin, TCF4/β-catenin, Toxoflavin, Toxoflavine

Field of Research

Epigenetics & Chromatin, Infectious Disease & Virology, Signal Transduction, Stem Cell & Developmental Biology

Purity

97.78% (May vary between batches)

Solubility

DMSO:25 mg/mL (129.43 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (10.35 mM)

Smiles

Cn1ncnc2c1nc (=O) n (C) c2=O

Molecular Formula

C7H7N5O2

Molecular Weight

193.16

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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