gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) Mouse Monoclonal Antibody
Product Specifications
Gene Name
[SILV]
NCBI Gene ID
6490
Reactivity
Human.<br>Others not tested
Storage Conditions
Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Specificity
By immunohistochemistry, it specifically recognizes a protein in melanocytes and melanomas. This MAb reacts with junctional and blue nevus cells and variably with fetal and neonatal melanocytes. Intradermal nevi, normal adult melanocytes, and non-melanocytic cells are negative. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin. Metastatic amelanotic melanoma can often be confused with a variety of poorly differentiated carcinomas, large cell lymphomas, and sarcomas using H & E stains alone. It is also difficult to differentiate melanoma from spindle cell carcinomas and various types of mesenchymal neoplasms. This MAb stains fetal and neonatal melanocytes, junctional and blue nevus cells, and malignant melanoma. This MAb also stains Angiomyolipoma (PEComa).
Other Gene Names
[PMEL; PMEL; P1; SI; SIL; ME20; P100; SILV; ME20M; gp100; ME20-M; PMEL17; D12S53E; D12S53E; PMEL17; SILV; ME20M; ME20-S; ME20S]
Short Name
[gp100 / Melanosome / PMEL17 / SILV]
Other Product Names
[melanocyte protein PMEL isoform 2; Melanocyte protein PMEL; melanocyte protein PMEL; premelanosome protein; ME20-M; ME20M]
NCBI GI Number
318037593
NCBI Accession Number
NP_001186982.1
NCBI GB Accession Number
NM_001200053.1
Uniprot Accession Number
P40967
CAS Number
9007-83-4
Available Sizes
Curated Selection
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