FR 122047
FR 122047 hydrochloride is a potent and selective cyclooxygenase-1 (COX-1) inhibitor, exhibiting an IC50 of 28 nM for human recombinant COX-1 versus 65 μM for COX-2. This small molecule is a valuable research tool for investigating COX-1-specific roles in physiological and pathophysiological processes, including platelet aggregation and gastric function, in both in vitro and ex vivo experimental models.
Product Specifications
CAS Number
130717-51-0
Product Name Alternative
Field of Research
Immunology & Inflammation, Neuroscience
Purity
99.63% (May vary between batches)
Solubility
DMSO:4 mg/mL (8.7 mM) ; H2O:2 mg/mL (4.35 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.17 mM)
Smiles
CN1CCN (CC1) C (=O) C2=NC (=C (S2) C3=CC=C (C=C3) OC) C4=CC=C (C=C4) OC.Cl
Molecular Formula
C23H26ClN3O3S
Molecular Weight
459.99
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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