RPI-1
RPI-1 is a potent and selective ATP-competitive inhibitor of the Ret tyrosine kinase. It is utilized in biochemical and cellular assays to investigate Ret-driven signaling pathways and has been employed in preclinical research models to study cancers like medullary thyroid carcinoma.
Product Specifications
CAS Number
269730-03-2
Product Name Alternative
Inhibitor, HGFR, medullary, inhibit, kinase, oral, PLCγ, Met, carcinoma, cells, cMet/HGFR, c-Met, cMet, cRET, CTND1, phosphorylation, thyroid, proliferation, RET, RPI 1, RPI1, RPI-1, tyrosine
Field of Research
Cell Biology, Metabolism Research, Neuroscience, Signal Transduction
Purity
≥95% (May vary between batches)
Solubility
DMSO:5.5 mg/mL (18.5 mM)
Smiles
COc1cc2NC (=O) \C (=C/c3ccc (O) cc3) c2cc1OC
Molecular Formula
C17H15NO4
Molecular Weight
297.31
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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