PX-12
PX-12 is a thioredoxin-1 (Trx-1) inhibitor that induces apoptosis and suppresses HIF-1α and VEGF, demonstrating antitumor activity in preclinical models. It is a research tool for studying cancer mechanisms and has been evaluated in clinical trials for advanced metastatic cancers.
Product Specifications
CAS Number
141400-58-0
Product Name Alternative
Inhibit, IV 2, IV2, IV-2, PX12, PX-12, PX 12, Inhibitor, TRX (HT-29 cells), TRX (MCF-7)
Field of Research
Cell Biology, Metabolism Research
Purity
98.00% (May vary between batches)
Solubility
H2O:< 1 mg/mL (insoluble or slightly soluble) ; Ethanol:38 mg/mL (201.79 mM) ; DMSO:48 mg/mL (254.9 mM)
Smiles
CCC (C) SSc1ncc[nH]1
Molecular Formula
C7H12N2S2
Molecular Weight
188.31
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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