HX 531
HX 531 is a potent RXR antagonist with an IC50 of 18 nM. It has been shown in murine studies to counteract high-fat diet-induced metabolic disorders, including obesity, insulin resistance, and diabetes, by lowering triglyceride accumulation in adipose tissue, skeletal muscle, and liver. This makes it a valuable research tool for investigating RXR pathways in metabolic disease models.
Product Specifications
CAS Number
188844-34-0
Product Name Alternative
Inhibit, Inhibitor, HX 531, HX531, HX-531, RAR/RXR, RXR, Retinoic acid receptors, Retinoid Receptor, Retinoid X receptors, RetinoidReceptor
Field of Research
Cell Biology, Metabolism Research
Purity
98.59% (May vary between batches)
Solubility
DMSO:150 mg/mL (310.2 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.07 mM)
Smiles
CN1c2ccc (cc2N=C (c2ccc (cc2) C (O) =O) c2cc3c (cc12) C (C) (C) CCC3 (C) C) [N+] ([O-]) =O
Molecular Formula
C29H29N3O4
Molecular Weight
483.56
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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