BIIB021
BIIB021 (CNF2024) is a potent, fully synthetic, and orally bioavailable HSP90 inhibitor with a Ki of 1.7 nM and an EC50 of 38 nM. This small molecule is a valuable research tool for studying HSP90's role in oncology and neurodegenerative diseases, demonstrating activity in both cellular and animal models of cancer.
Product Specifications
CAS Number
848695-25-0
Product Name Alternative
CNF2024
Field of Research
Cancer Biology, Cell Biology, Protein Biochemistry
Purity
>98%
Bioactivity
HSP90 Inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 25 mg/ml)
Smiles
COc1c (C) cnc (Cn2cnc3c (Cl) nc (N) nc23) c1C
Molecular Formula
C14H15ClN6O
Molecular Weight
318.8
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
6-Chloro-9-[ (4-methoxy-3,5-dimethylpyridin-2-yl) methyl]purin-2-amine
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